CD153 antibodies, mouse

CD153 antibodies, mouse

Clone: REA1083 | Dilution: 1:50
Clone REA1083 recognizes the mouse CD153 (CD30 ligand) antigen, a 40 kDa type II membrane protein belonging to the NGF/TNF superfamily. It is expressed by activated CD4
+
and CD8
+
T cells. The interaction between CD30 and CD153 enhance the proliferation of stimulated T cells but in the presence of the REA1083 antibody this effect is blocked.
In vivo
treatment with this antibody is reported to inhibit or delay immune reactions.
Additional information: Clone REA1083 displays negligible binding to Fc receptors.

Alternative names

TNFSF8, CD30LG, CD30L

Technical specifications

  • Antigen: CD153
  • Clone: REA1083
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TNFSF8, CD30LG, CD30L
  • Entrez Gene ID: 21949
  • Molecular mass of antigen [kDa]: 27
  • Distribution of antigen: B cells, bone marrow, eosinophils, granulocytes, macrophages, monocytes, myeloid cells, neutrophils, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE-Vio615, VioBright 515, Biotin, APC, PE
  • Selected references

    1. al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26(8): 1695-1699
    2. Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J. Immunol. 162(12): 7058-7066
    3. Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J. Immunol. 167: 6669-6677
Product options: 9
130-118-431

CD153-PE, mouse

30 µg in 200 µL (1)
CHF  85.00
130-118-432

CD53-APC, mouse

30 µg in 200 µL (1)
CHF  85.00
130-118-278

CD153-APC, mouse

150 µg in 1 mL (1)
CHF  250.00
30 µg in 200 µL (1)
CHF  110.00
150 µg in 1 mL (1)
CHF  325.00
30 µg in 200 µL (1)
CHF  160.00
150 µg in 1 mL (1)
CHF  460.00
30 µg in 200 µL (1)
CHF  45.00
150 µg in 1 mL (1)
CHF  130.00