CD140b antibodies, mouse

CD140b antibodies, mouse

Clone: REA634 | Dilution: 1:10
Clone REA634 recognizes the mouse CD140b antigen, also known as platelet-derived growth factor receptor-β (PDGFR-β), a tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB. CD140b plays a role in the regulation of embryonic development, cell proliferation, differentiation, chemotaxis, survival, and migration. CD140b is expressed on embryonic tissues and mesenchymal-derived cells in adult mice.
Additional information: Clone REA634 displays negligible binding to Fc receptors.

Alternative names

PDGF-R-beta, PDGFR-beta, PDGFR-1

Technical specifications

  • Antigen: CD140b
  • Clone: REA634
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: PDGF-R-beta, PDGFR-beta, PDGFR-1
  • Entrez Gene ID: 18596
  • Molecular mass of antigen [kDa]: 120
  • Distribution of antigen: other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, APC, PE-Vio770, Biotin
  • Selected references

    1. Tallquist, M. D. et al. (2003) Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol. 1(2): E52
    2. Taneda, S. et al. (2003) Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury. J. Am. Soc. Nephrol. 14(10): 2544-2555
    3. Seifert, R. A. et al. (1993) PDGF-AB requires PDGF receptor alpha-subunits for high-affinity, but not for low-affinity, binding and signal transduction. J. Biol. Chem. 268(6): 4473-4480
Product options: 6
9 µg in 300 µL (1)
CHF  68.00
30 µg in 1 mL (1)
CHF  116.00
9 µg in 300 µL (1)
CHF  79.00
30 µg in 1 mL (1)
CHF  116.00
9 µg in 300 µL (1)
CHF  29.00
30 µg in 1 mL (1)
CHF  47.00

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