CD11b/c antibodies, rat

CD11b/c antibodies, rat

Clone: REA325 | Dilution: 1:50
Clone REA325 recognizes the rat CD11b and c antigen, which are both single-pass type I membrane glycoproteins also known as integrin α-M (CD11b) and integrin α-X (CD11c). CD11c and CD11b are expressed on monocytes, granulocytes, macrophages, dendritic cells, NK cells, and a subset of lymphocytes.
Additional information: Clone REA325 displays negligible binding to Fc receptors.

Alternative names

ITGAM, ITGAX, Leukocyte adhesion glycoprotein p150,95 α chain (Leukocyte adhesion receptor p150,95), RGD1561123, CR-3 α chain, Cell surface glycoprotein MAC-1 subunit α, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b

Technical specifications

  • Antigen: CD11b/c
  • Clone: REA325
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: ITGAM, ITGAX, Leukocyte adhesion glycoprotein p150,95 α chain (Leukocyte adhesion receptor p150,95), RGD1561123, CR-3 α chain, Cell surface glycoprotein MAC-1 subunit α, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b
  • Entrez Gene ID: 25021, 499271
  • Molecular mass of antigen [kDa]: 128
  • Distribution of antigen: monocytes, granulocytes, macrophages, dendritic cells, NK cells, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, APC-Vio770, PE-Vio770
  • Selected references

    1. Hubert, F. X. et al. (2004)
      Rat plasmacytoid dendritic cells are an abundant subset of MHC Class II
      +
      CD4
      +
      CD11b
      OX62
      and type I IFN-producing cells that exhibit selective expression of Toll-like receptors 7 and 9 and strong responsiveness to CpG.
      J. Immunol. 172(12): 7485-7494
    2. Kriegel, M. A. et al. (2012)
      Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c
      +
      CD11b
      +
      dendritic cells.
      Proc. Natl. Acad. Sci. U.S.A. 109(9): 3457-3462
    3. Milling, S. et al. (2010) Subsets of migrating intestinal dendritic cells. Immunol. Rev. 234(1): 259-267
Product options: 5
130-120-288

CD11b/c-APC, rat

30 µg in 200 µL (1)
CHF  85.00
130-120-214

CD11b/c-APC, rat

150 µg in 1 mL (1)
CHF  250.00
30 µg in 200 µL (1)
CHF  110.00
150 µg in 1 mL (1)
CHF  325.00
30 µg in 200 µL (1)
CHF  110.00

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