CD105 antibodies, human

CD105 antibodies, human

Clone: REA794 | Dilution: 1:50
Clone REA794 recognizes the CD105 antigen, also known as endoglin, which serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3. An epitope of CD105 is recognized by the SH-2 antibody, which was raised against human mesenchymal stromal cells (MSC) that show mesodermal differentiation capacity. Therefore, it can be used for studies on mesengenesis. CD105 is also expressed on mature endothelial cells and on some leukemic cells of B lymphoid and myeloid origin.
Additional information: Clone REA794 displays negligible binding to Fc receptors.

Alternative names

ENG, END, HHT1, ORW1, Endoglin

Technical specifications

  • Antigen: CD105
  • Clone: REA794
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ENG, END, HHT1, ORW1, Endoglin
  • Entrez Gene ID: 2022
  • Molecular mass of antigen [kDa]: 68
  • Distribution of antigen: bone marrow, endothelial cells, leukemia cells, mesenchymal stem cells, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Bellón, T. et al. (1993) Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions. Eur. J. Immunol. 23(9): 2340-2345
    2. Barry, F. P. et al. (1999) The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105). Biochem. Biophys. Res. Commun. 265: 134-139
    3. Majumdar, M. K. et al. (2000) Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells. J. Cell. Physiol. 185: 98-106
Product options: 18
130-112-327

CD105-FITC, human

for 30
tests
(1)
CHF  100.00
130-112-169

CD105-FITC, human

for 100
tests
(1)
CHF  245.00
130-112-321

CD105-PE, human

for 30
tests
(1)
CHF  120.00
130-112-163

CD105-PE, human

for 100
tests
(1)
CHF  290.00
130-112-324

CD105-APC, human

for 30
tests
(1)
CHF  120.00
130-112-166

CD105-APC, human

for 100
tests
(1)
CHF  290.00
130-112-320

CD105-VioBlue, human

for 30
tests
(1)
CHF  125.00
130-112-162

CD105-VioBlue, human

for 100
tests
(1)
CHF  305.00
130-112-322

CD105-PE-Vio615, human

for 30
tests
(1)
CHF  130.00
130-112-164

CD105-PE-Vio615, human

for 100
tests
(1)
CHF  315.00
130-112-325

CD105-PE-Vio770, human

for 30
tests
(1)
CHF  130.00
130-112-167

CD105-PE-Vio770, human

for 100
tests
(1)
CHF  315.00
130-112-326

CD105-APC-Vio770, human

for 30
tests
(1)
CHF  130.00
130-112-168

CD105-APC-Vio770, human

for 100
tests
(1)
CHF  315.00
130-112-328

CD105-PerCP-Vio700, human

for 30
tests
(1)
CHF  130.00
130-112-170

CD105-PerCP-Vio700, human

for 100
tests
(1)
CHF  315.00
130-112-319

CD105-Biotin, human

for 30
tests
(1)
CHF  100.00
130-112-161

CD105-Biotin, human

for 100
tests
(1)
CHF  245.00

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