CD101 antibodies, human

CD101 antibodies, human

Clone: REA954 | Dilution: 1:50
Clone REA954 recognizes the human CD101 antigen, also known as V7 or IGSF2, which is a 140 kDa type I transmembrane glycoprotein of the Ig gene superfamily. CD101 is expressed on monocytes, granulocytes, and subsets of dendritic cells (DCs). In addition, CD101 is expressed on certain subpopulations of T cells, in particular about 5–30% of FoxP3
+
Treg cells in peripheral blood. The interaction of CD101 with clone REA954 has been shown to inhibit T cell activation by allogeneic DCs or CD3 antibodies.
Additional information: Clone REA954 displays negligible binding to Fc receptors.

Alternative names

EWI-101, IGSF2, V7, p126

Technical specifications

  • Antigen: CD101
  • Clone: REA954
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: EWI-101, IGSF2, V7, p126
  • Entrez Gene ID: 9398
  • Molecular mass of antigen [kDa]: 113
  • Distribution of antigen: dendritic cells, granulocytes, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, PE-Vio770, VioBright 515, Biotin
  • Selected references

    1. Rivas, A. et al. (1995) V7, a novel leukocyte surface protein that participates in T cell activation. J. Immunol. 154: 4423-4433
    2. Soares, L. R. et al. (1998)
      V7 (CD101) ligation inhibits TCR/CD3-induced IL-2 production by blocking Ca
      2+
      flux and nuclear factor of activated T cell nucleartranslocation.
      J. Immunol. 161: 209-217
    3. Bouloc, A. et al. (2000) Triggering CD101 molecule on human cutaneous dendritic cells inhibits T cell proliferation via IL-10 production. Eur. J. Immunol. 30: 3132-3139
Product options: 12
130-115-902

CD101-PE, human

for 30
tests
(1)
CHF  120.00
130-115-830

CD101-PE, human

for 100
tests
(1)
CHF  290.00
130-115-903

CD101-APC, human

for 30
tests
(1)
CHF  120.00
130-115-831

CD101-APC, human

for 100
tests
(1)
CHF  290.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  165.00
for 100
tests
(1)
CHF  395.00
for 30
tests
(1)
CHF  100.00
for 100
tests
(1)
CHF  245.00