Anti-Slan (M-DC8) antibodies, human

Anti-Slan (M-DC8) antibodies, human

Clone: DD-1 | Dilution: 1:50
The Anti-Slan (M-DC8) antibody (clone DD-1) recognizes 6-Sulfo LacNAc (Slan), which is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1). This antigen is characteristically expressed on a new subset of peripheral blood mononuclear cells (PBMCs) with features closely related to CD16
+
CD14
low
monocytes.
Slan (M-DC8)
+
cells constitute 0.5–2% of all PBMCs with similar frequencies among mononuclear cells from cord blood.

Alternative names

SELPLG, CD162, CLA, PSGL-1, PSGL1

Technical specifications

  • Antigen: Slan (M-DC8)
  • Clone: DD-1
  • Isotype: mouse IgMκ
  • Isotype control: Mouse IgM – isotype control antibodies
  • Alternative names of antigen: SELPLG, CD162, CLA, PSGL-1, PSGL1
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, Biotin
  • Selected references

    1. Schäkel, K. et al. (2002) 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells. Immunity 17: 289-301
    2. de Baey, A. et al. (2001)
      Phenotype and function of human dendritic cells derived from M-DC8
      +
      monocytes.
      Eur. J. Immunol. 31: 1646-1655
    3. Schäkel, K. et al. (1998)
      A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and
      in vitro
      priming of cytotoxic T lymphocytes.
      Eur. J. Immunol. 28: 4084-4093
Product options: 10
for 30
tests
(1)
CHF  105.00
for 100
tests
(1)
CHF  250.00
for 30
tests
(1)
CHF  125.00
for 100
tests
(1)
CHF  295.00
for 30
tests
(1)
CHF  125.00
for 100
tests
(1)
CHF  295.00
for 30
tests
(1)
CHF  125.00
for 100
tests
(1)
CHF  305.00
for 30
tests
(1)
CHF  105.00
for 100
tests
(1)
CHF  250.00

Related products

5 products available | view all