Anti-Mesothelin antibodies, human

Anti-Mesothelin antibodies, human

Clone: REA1057 | Dilution: 1:50
Clone REA1057 recognizes the human mesothelin antigen, a membrane glycoprotein also known as CAK1 or pre-pro-megakaryocyte-potentiating factor. Mesothelin is expressed on mesothelial cells and overexpressed on different tumors, e.g., mesotheliomas and adenocarcinomas. Mesothelin is a precursor protein which has functions in cellular adhesion.
Additional information: Clone REA1057 displays negligible binding to Fc receptors.

Alternative names

CAK1, MPF, MSLN

Technical specifications

  • Antigen: Mesothelin
  • Clone: REA1057
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CAK1, MPF, MSLN
  • Entrez Gene ID: 10232
  • Molecular mass of antigen [kDa]: 35
  • Distribution of antigen: tumor cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Hassan, R. et al. (2004) Mesothelin: a new target for immunotherapy. Clin. Cancer Res. 10(12 Pt 1): 3937-3942
    2. Onda, M. et al. (2006) Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma. Clin. Cancer Res. 12(14 Pt 1): 4225-4231
    3. Iwahori, K. et al. (2008) Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin. Lung Cancer 62(1): 45-54
Product options: 8
for 30
tests
(1)
CHF  105.00
for 100
tests
(1)
CHF  250.00
for 30
tests
(1)
CHF  125.00
for 100
tests
(1)
CHF  295.00
for 30
tests
(1)
CHF  125.00
for 100
tests
(1)
CHF  295.00
for 30
tests
(1)
CHF  105.00
for 100
tests
(1)
CHF  250.00