Anti-Jagged2 antibodies, mouse

Anti-Jagged2 antibodies, mouse

Clone: HMJ2-1 | Dilution: 1:10
The HMJ2-1 monoclonal antibody recognizes mouse Jagged2, a transmembrane protein also called JAG2. Jagged 2 is one of five Notch receptor ligands expressed on thymic lymphoid and stromal cells, splenic DCs and macrophages but not on B cells. It is reported that Jagged 2 promotes metastasis in lung by increasing the expression of GATA binding factors.

Alternative names

JAG2, D12Ggc2e, Serh, mJagged2-1, sm

Technical specifications

  • Antigen: Jagged2
  • Clone: HMJ2-1
  • Isotype: hamster IgG
  • Alternative names of antigen: JAG2, D12Ggc2e, Serh, mJagged2-1, sm
  • Entrez Gene ID: 16450
  • Molecular mass of antigen [kDa]: 132
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, Biotin, PE
  • Selected references

    1. Yang, Y. et al. (2011)
      Treatment of acute myeloid leukemia cells
      in vitro
      with a monoclonal antibody recognizing a myeloid differentiation antigen allows normal progenitor cells to be expressed.
      J. Clin. Invest. 121(4): 1373-1385
    2. Moriyama, Y. et al. (2008) Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice. Int. Immunol. 20: 763-773
    3. Sekine, C. et al. (2009) Differential regulation of splenic CD8– dendritic cells and marginal zone B cells by Notch ligands. Int. Immunol. 21: 295-301
Product options: 3
30 µg in 1 mL (1)
CHF  89.00
30 µg in 1 mL (1)
CHF  89.00
30 µg in 1 mL (1)
CHF  47.00