REAlease® CD4/CD8 (TIL) MicroBead Kit, human

REAlease
®
CD4/CD8 (TIL) MicroBead Kit
, human

The REAlease
®
CD4/CD8 (TIL) MicroBead Kit,human has been developed for positive selection of CD4
+
and CD8
+
tumor-infiltrating leukocytes (TILs) from single-cell suspensions of solid human tumors as well as xenotransplanted tumors of mice with a humanized immune system. The kit contains an indirect magnetic labeling system for obtaining target cells free of MicroBeads and REAlease Biotin Complex.

Background information

The REAlease
®
CD4/CD8 (TIL) MicroBead Kit has been developed for the isolation of CD4
+
and CD8
+
tumor-infiltrating leukocytes (TILs) from single-cell suspensions of solid human tumors as well as xenotransplanted tumors of mice with a humanized immune system. CD4 is expressed on T helper cells, at a lower level on monocytes and dendritic cells, and at a very low level on hematopoietic progenitor cells. CD8 is expressed on cytotoxic T cells.
The REAlease CD4/CD8 (TIL) MicroBead Kit is an indirect magnetic labeling system that allows to obtain cells free of MicroBeads and the REAlease Biotin Complex.

Downstream applications

  • Isolation of specific CD4+ and CD8+ tumor-infiltrating T cell subsets. The selected CD4+ and CD8+ T cell populations can be sorted according to a second marker of interest, for example, CD137 (4-1BB), CD223 (LAG-3), CD279 (PD1), or CD366 (TIM-3).
  • Isolation of CD4+ and CD8+ tumor-infiltrating T cells which need to be label-free.
Product options: 1
for 5×
10
8
total cells
CHF  720.00

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