CD144 (VE-Cadherin) MicroBeads, human

CD144 (VE-Cadherin) MicroBeads, human

CD144 (VE-Cadherin) MicroBeads have been developed for the positive selection or depletion of CD144
endothelial cells from differentiated ES or iPS cell cultures.

Background information

CD144, also known as VE-Cadherin or Cadherin-5, is a member of the cadherin family of calcium-dependent adhesion molecules. The antigen is expressed on endothelial cells
in vivo
in vitro1,2
and has been used for the isolation of endothelial cells derived from embryonic stem cells and induced pluripotent stem cells
. It is known to be involved in homophilic cell interactions contributing to the cohesion and organization of the intercellular junctions of the vascular endothelium and thought to play a role in vascular permeability and remodeling. CD144 MicroBeads react with a calcium-independent epitope on CD144.


For positive selection: LS or autoMACS
Columns. For depletion: LD or autoMACS Columns.
  • Selected references

    1. Rufaihah, A. J. et al. (2011) Arterioscler. Thromb. Vasc. Biol. 3: e72-e79
    2. Tatsumi, R. et al. (2011) Simple and highly efficient method for production of endothelial cells from human embryonic stem cells. Cell Transplant 20: 1423-1430
    3. Patsch, C. et al. (2015) Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells. Nat. Cell Biol. 17(8): 994-1003
    4. Thoma E.C. et al. (2016) Establishment of a translational endothelial cell model using directed differentiation of induced pluripotent stem cells from Cynomolgus monkey. Sci. Rep. 6: 35830
Product options: 1
for 1×
total cells
CHF  759.00