Clone:
REA682
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
Forkhead box protein P1

Specifications for FoxP1 Antibody, anti-human/mouse, REAfinity™

Overview

Clone REA682 recognizes the human and mouse transcription repressor FoxP1, also known as forkhead box protein P1. It is involved in the specification and differentiation of lung, brain, thymus, and heart epithelium and is an essential transcriptional regulator of B cell development. FoxP1 is expressed in different tissues, e.g., tonsil, spleen, thymus, epithelium, kidney, blood, and motor neurons.
Additional information: Clone REA682 displays negligible binding to Fc receptors.

Alternative names

Forkhead box protein P1

Detailed product information

Technical specifications

CloneREA682
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
Cross-reactivityzebrafish
AntigenFoxP1
Alternative names of antigenForkhead box protein P1
Molecular mass of antigen [kDa]75, 79(separately shown for human and mouse/rat)
Distribution of antigenB cells, lung cancer cells, brain, heart
Entrez Gene ID27086 , 108655
RRIDAB_2651762, AB_2651763, AB_2651764, AB_2651761

References for FoxP1 Antibody, anti-human/mouse, REAfinity™

Publications

  1. van Keimpema, M. et al. (2014) FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells. Blood 124(23): 3431-3440
  2. Banham, A. H. et al. (2001) The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p. Cancer Res. 61(24): 8820-8829
  3. Ackermann, S. et al. (2014) FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma. BMC Cancer 14: 1471-2470

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