Clone:
REA678
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CD97

Specifications for CD97v2 Antibody, anti-mouse, REAfinity™

Overview

Clone REA678 recognizes the mouse CD97 antigen variant 2 (CD97v2).CD97 is a member of the EGF-TM7 family, which is a group of class II seven-span transmembrane receptors expressed ubiquitously, but mainly expressed by cells of the immune system. CD97 has seven putative transmembrane domains. It has an extended extracellular segment containing several adhesion molecule structure motifs, and has been shown to interact with the human DAF (CD55). The variant 2 of CD97 exhibits a 94 aa deletion that results in loss of the third EGF-like repeat.
Additional information: Clone REA678 displays negligible binding to Fc receptors.

Alternative names

CD97

Detailed product information

Technical specifications

CloneREA678
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD97v2
Alternative names of antigenCD97
Molecular mass of antigen [kDa]88
Distribution of antigenother
Entrez Gene ID26364
RRIDAB_2659675, AB_2659676, AB_2659677, AB_2659678, AB_2659679, AB_2659674

References for CD97v2 Antibody, anti-mouse, REAfinity™

Publications

  1. Leemans, J. C. et al. (2004) The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense. J. Immunol. 172(2): 1125-1131
  2. Hamann, J. et al. (2000) Molecular cloning and characterization of mouse CD97. Int. Immunol. 12(4): 439-448
  3. Qian, Y. M. et al. (1999) Structural characterization of mouse CD97 and study of its specific interaction with the murine decay-accelerating factor (DAF, CD55). Immunology 98(2): 303-311

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