Clone:
REA627
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, 2610028K12Rik, E430033M20Rik, Mtvr1

Specifications for CD71 Antibody, anti-mouse, REAfinity™

Overview

Clone REA627 recognizes the mouse CD71 cell-surface antigen, which is also known as transferrin receptor protein 1 (TfR1), and essential for iron transport into proliferating cells. This homodimer is a single-pass type II membrane protein, which is able to bind one transferrin molecule per 90 kDa subunit. CD71 plays a role in cell proliferation by controlling the supply of iron and is expressed on erythroid precursors, immature proliferating cells, reticulocytes, but is very low expressed on resting leukocytes.
Additional information: Clone REA627 displays negligible binding to Fc receptors.

Alternative names

Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, 2610028K12Rik, E430033M20Rik, Mtvr1

Detailed product information

Technical specifications

CloneREA627
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD71
Alternative names of antigenTransferrin receptor protein 1, TR, TfR, TfR1, Trfr, 2610028K12Rik, E430033M20Rik, Mtvr1
Molecular mass of antigen [kDa]86
Distribution of antigenleukocytes, hematopoietic stem and progenitor cells
Entrez Gene ID22042
RRIDAB_2784273, AB_2751633, AB_2659130, AB_2659131, AB_2659132, AB_2659133, AB_2659134, AB_2659135, AB_2659136, AB_2659137, AB_2784274

References for CD71 Antibody, anti-mouse, REAfinity™

Publications

  1. Lesley, J. et al. (1984) Expression of transferrin receptor on murine hematopoietic progenitors. Cell. Immunol. 83(1): 14-25
  2. Koulnis, M. et al. (2011) Identification and analysis of mouse erythroid progenitors using the CD71/TER119 flow-cytometric assay. J. Vis. Exp. 5(54)
  3. Levy, J. E. et al. (1999) Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat. Genet. 21(4): 396-399

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