Adult brain workflow - 
Isolation and analysis of neural cells

We offer comprehensive solutions for each step of your neural cell research, providing extensive, automated support for the viability of your cells. Whether you rely on the ability to conduct a full workflow isolation and analysis of neural cells from adult rodent brain (older than P7) to generating highly purified neural cells from the adult brain in just half a day, our solutions provide you highly viable cell lines compatible with many downstream applications, such as single-cell sequencing or flow cytometric analysis.

Our adult brain workflow offers a fast, easy solution to isolate and analyze neural cells from adult rodent brain (>P7). Using the Adult Brain Dissociation Kit, mouse and rat with our gentleMACS™ Octo Dissociator with Heaters, gently dissociates brain tissue obtaining highly pure and viable neural cells.  Your neural cells of interest can then be isolated with our MicroBeads. These isolated cells are ready for downstream applications, including cell cultivation or analysis with optimized neural media and specific antibodies. 

• Falcão, A. M. et al. (2018) Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis. Nat. Med. 24(12): 18371844.
• Bennett, R. E. et al. (2018) Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 115(6): 1289-1298.
• Vicente-Gutierrez C. et al. (2019) Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour. Nat Metab. 1(2):201-211.
• Hopp S. C. et al. (2019) The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease. J Neuroinflammation. 15(1):269.
• Early A. N. et al. (2020) Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice. J Neuroinflammation. 17(1):115.