CD93 antibodies, human

CD93 antibodies, human

Clone: VIMD2 | Dilution: 1:11
The monoclonal antibody VIMD2 reacts with human CD93, also known as C1qRp, which is a 120 kDa heavily O-glycosylated protein. It is expressed on myeloid cells, platelets, endothelial cells, and immature dendritic cells whereas mature dendritic cells show weak to negative CD93 expression. C1qRp is involved in regulation of phagocytic activity, macrophage activation, and cell-cell adhesion.

Alternative names

C1QR1, C1qR(P), C1qRp, CDw93, ECSM3, MXRA4, dJ737E23.1

Technical specifications

  • Antigen: CD93
  • Clone: VIMD2
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: C1QR1, C1qR(P), C1qRp, CDw93, ECSM3, MXRA4, dJ737E23.1
  • Entrez Gene ID: 22918
  • Molecular mass of antigen [kDa]: 66
  • Cross-reactivity:
    chimpanzee (
    Pan troglodytes
    )
    ,
    olive baboon (
    Papio anubis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: endothelial cells, granulocytes, monocytes, myeloid cells, NK cells, platelets
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770, Biotin, FITC
  • Selected references

    1. Nepomuceno, R. R. and Tenner, A. J. (1998) C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets. J. Immunol. 160: 1929-1935
    2. Nepomuceno, R. R. et al. (1999) C1qRP Is a heavily O-glycosylated cell surface protein involved in the regulation of phagocytic activity. J. Immunol. 162: 3583-3589
    3. Steinberger, P. et al. (2002) Identification of human CD93 as the phagocytic C1q receptor (C1qRp) by expression cloning. J. Leukoc. Biol. 71: 133-140
Product options: 8
130-098-431

CD93-FITC, human

for 100
tests
(1)
-
130-098-436

CD93-PE, human

for 100
tests
(1)
-
130-098-441

CD93-APC, human

for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 100
tests
(1)
-

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