CD84 antibodies, human

CD84 antibodies, human

Clone: REA1102 | Dilution: 1:50
Clone REA1102 recognizes the human CD84 antigen, a 65–80 kDa single-chain surface glycoprotein and member of the CD2 subset of the immunoglobulin (Ig) superfamily. CD84 is expressed on granulocytes, monocytes, macrophages, B cells, platelets, antigen-presenting cells, and subsets of T cells including thymocytes and mature T cells. Homophilic ligation of CD84 or ligation with CD84 antibodies has been shown to lead to enhanced proliferation of T cells as well as IFN-γ secretion.
Additional information: Clone REA1102 displays negligible binding to Fc receptors.

Alternative names

Ly9b, SLAMF5, hCD84, GR6

Technical specifications

  • Antigen: CD84
  • Clone: REA1102
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ly9b, SLAMF5, hCD84, GR6
  • Entrez Gene ID: 8832
  • Molecular mass of antigen [kDa]: 36
  • Distribution of antigen: B cells, granulocytes, macrophages, monocytes, platelets, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, Biotin
  • Selected references

    1. de la Fuente, M. A. et al. (1997) CD84 leukocyte antigen is a new member of the Ig superfamily. Blood 90: 2398-2405
    2. Martin, M. et al. (2001) CD84 functions as a homophilic adhesion molecule and enhances IFN-γ secretion: adhesion is mediated by Ig-like domain 1. J. Immunol. 167: 3668-3676
    3. Tangye, S. G. et al. (2003) Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation. J. Immunol. 171: 2485-2495
    4. Zaiss, M. et al. (2003) CD84 expression on human hematopoietic progenitor cells. Exp. Hematol. 31: 798-805
Product options: 12
130-119-211

CD84-FITC, human

for 30
tests
(1)
-
130-119-034

CD84-FITC, human

for 100
tests
(1)
-
130-119-212

CD84-PE, human

for 30
tests
(1)
-
130-119-035

CD84-PE, human

for 100
tests
(1)
-
130-119-213

CD84-APC, human

for 30
tests
(1)
-
130-119-036

CD84-APC, human

for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-

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