CD6 antibodies, human

CD6 antibodies, human

Clone: REA1075 | Dilution: 1:50
Clone REA1075 recognizes the human CD6 antigen, a 100 kDa transmembrane glycoprotein. CD6 is expressed on the majority of T cells as well as on a subset of B cells in peripheral blood. The CD6 antigen is also expressed at low levels on immature thymocytes and at high levels on mature thymocytes. CD6 functions as an adhesion molecule as well as costimulatory molecule for TCR-mediated T cell activation.
Additional information: Clone REA1075 displays negligible binding to Fc receptors.

Alternative names

TP120, T12

Technical specifications

  • Antigen: CD6
  • Clone: REA1075
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TP120, T12
  • Entrez Gene ID: 923
  • Molecular mass of antigen [kDa]: 70
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, neurons, T cells, CNS cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Bowen, M. A. et al. (1995) Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J. Exp. Med. 181: 2213-2220
    2. Hassan, N. J. et al. (2004) Frontline: Optimal T cell activation requires the engagement of CD6 and CD166. Eur. J. Immunol. 34(4): 930-940
Product options: 20
130-118-741

CD6-FITC, human

for 30
tests
(1)
-
130-118-619

CD6-FITC, human

for 100
tests
(1)
-
130-118-742

CD6-PE, human

for 30
tests
(1)
-
130-118-620

CD6-PE, human

for 100
tests
(1)
-
130-118-743

CD6-APC, human

for 30
tests
(1)
-
130-118-621

CD6-APC, human

for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-

Related products

3 products available