CD58 (LFA-3) antibodies, human

CD58 (LFA-3) antibodies, human

Clone: REA1098 | Dilution: 1:50
Clone REA1098 recognizes human CD58, a 45–70 kDa cell surface molecule which is a member of the immunoglobin superfamily. It is expressed on professional APCs (antigen-presenting cells) such as B cells, dendritic cells, macrophages, and epithelial cells as well as on T cells, monocytes, erythrocytes, endothelial cells, and fibroblasts. LFA-3 interacts with CD2 on T cells and is important for interaction between T cells and professional APCs.
Additional information: Clone REA1098 displays negligible binding to Fc receptors.

Alternative names

LFA-3, ag3

Technical specifications

  • Antigen: CD58 (LFA-3)
  • Clone: REA1098
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LFA-3, ag3
  • Entrez Gene ID: 965
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, epithelial cells, fibroblasts, macrophages, monocytes, T cells, red blood cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, VioBright 515
  • Selected references

    1. Sanchez-Madrid, F. et al. (1982) Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U.S.A. 79: 7489-7493
    2. Dengler, T. J. et al. (1992) Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3). Eur. J. Immunol. 22(11): 2809-2817
    3. Wang, J. H. et al. (1999) Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. Cell 97(6): 791-803
Product options: 8
for 30
tests
(1)
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for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-