CD45RB antibodies, human

CD45RB antibodies, human

Clone: REA119 | Dilution: 1:11
Clone REA119 recognizes CD45RB, which is a splice variant isoform of CD45, the leukocyte common antigen (LCA). CD45 is a haemopoietic cell specific protein tyrosine phosphatase, and regulates various signaling events through cytokine receptors and in response to cellular adhesion. Expression of CD45RB is found on T cell subset, B cells, monocytes/macrophages, granulocytes, and dendritic cells.
Additional information: Clone REA119 displays negligible binding to Fc receptors.

Alternative names

Ptprc, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200

Technical specifications

  • Antigen: CD45RB
  • Clone: REA119
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ptprc, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
  • Entrez Gene ID: 5788
  • Molecular mass of antigen [kDa]: 145
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: B cells, NK cells, myeloid cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Parikh, K. et al. (2009) Extracellular ligation-dependent CD45RB enzymatic activity negatively regulates lipid raft signal transduction. Blood 113: 594-603
    2. Dianzani, U. et al. (1992) Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes. Eur. J. Immunol. 22(2): 365-371
Product options: 14
for 30
tests
(1)
-
for 100
tests
(1)
-
130-100-398

CD45RB-PE, human

for 30
tests
(1)
-
130-100-399

CD45RB-PE, human

for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-

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