CD352 (NTB-A) antibodies, mouse

CD352 (NTB-A) antibodies, mouse

Clone: 13G3 | Dilution: 1:10
Clone 13G3 recognizes the mouse CD352 antigen, a single-pass type I membrane protein, also known as SLAM family member 6 (SLAM6) or NK, T, and B cell antigen (NTB-A) belonging to the CD2 subfamily of the immunoglobulin superfamily. It is expressed on NK, T, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases. CD352 plays a role in NK cell cytotoxicity and T cell cytokine responses. It controls neutrophil functions and serves as a regulator of both innate and adaptive immune responses.

Alternative names

SLAM family receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6

Technical specifications

  • Antigen: CD352 (NTB-A)
  • Clone: 13G3
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: SLAM family receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6
  • Entrez Gene ID: 30925
  • Molecular mass of antigen [kDa]: 36
  • Distribution of antigen: NK cells, B cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Peck, S. R. et al. (2000) Ly108: a new member of the mouse CD2 family of cell surface proteins. Immunogenetics 52(1-2): 63-72
    2. Howie, D. et al. (2005) Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J. Immunol. 174(10): 5931-5935
    3. Griewank, K. et al. (2007) Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 27(5): 751-762
Product options: 12
9 µg in 300 µL (1)
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30 µg in 1 mL (1)
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9 µg in 300 µL (1)
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30 µg in 1 mL (1)
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9 µg in 300 µL (1)
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30 µg in 1 mL (1)
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9 µg in 300 µL (1)
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30 µg in 1 mL (1)
-
9 µg in 300 µL (1)
-
30 µg in 1 mL (1)
-
9 µg in 300 µL (1)
-
30 µg in 1 mL (1)
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