CD22 antibodies, mouse

CD22 antibodies, mouse

Clone: REA1187 | Dilution: 1:50
Clone REA1187 recognizes the 150 kDa B cell–restricted glycoprotein CD22 on mice strains having the Lyb-8.2 alloantigen, e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, and SWR. Lyb-8.2 is expressed at mature levels on all B cell subsets. In bone marrow, CD22 is not detectable on pro–B cells, pre–B cells, and emerging IgM
+
B cells. CD22 plays a strong role in cell interactions and B cell activation.
Additional information: Clone REA1187 displays negligible binding to Fc receptors.

Alternative names

BL-CAM, SIGLEC-2, Lyb-8

Technical specifications

  • Antigen: CD22
  • Clone: REA1187
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: BL-CAM, SIGLEC-2, Lyb-8
  • Entrez Gene ID: 12483
  • Molecular mass of antigen [kDa]: 94
  • Distribution of antigen: B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, PE-Vio770, VioBright 515, Biotin
  • Selected references

    1. Symington, F. W. et al. (1982) Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody. Immunogenetics 16(5): 381-391
    2. Law, C. L. et al. (1994) Regulation of lymphocyte activation by the cell-surface molecule CD22. Immunol. Today 15(9): 442-449
    3. Erickson, L. D. et al. (1996) Differential expression of CD22 (Lyb8) on murine B cells. Immunogenetics 8(7): 1121-1129
Product options: 12
130-122-045

CD22-PE, mouse

30 µg in 200 µL (1)
-
130-122-038

CD22-PE, mouse

150 µg in 1 mL (1)
-
130-122-046

CD22-APC, mouse

30 µg in 200 µL (1)
-
130-122-039

CD22-APC, mouse

150 µg in 1 mL (1)
-
30 µg in 200 µL (1)
-
150 µg in 1 mL (1)
-
30 µg in 200 µL (1)
-
150 µg in 1 mL (1)
-
30 µg in 200 µL (1)
-
150 µg in 1 mL (1)
-
30 µg in 200 µL (1)
-
150 µg in 1 mL (1)
-

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