CD179b antibodies, human

CD179b antibodies, human

Clone: REA1066 | Dilution: 1:50
Clone REA1066 recognizes the CD179b antigen-like family member B, also known as immunoglobulin lambda like polypeptide (IGLL1). CD179b is expressed on pro–B and pre–B cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the pro–B cell to the pre–B cell stage, allelic exclusion at the Ig heavy chain gene locus, and support of Ig light chain gene rearrangements. The gene encoding for CD179b, as a B cell receptor, belongs to the immunoglobulin gene superfamily.
Additional information: Clone REA1066 displays negligible binding to Fc receptors.

Alternative names

lambda-5, IGLL1, IGL1

Technical specifications

  • Antigen: CD179b
  • Clone: REA1066
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: lambda-5, IGLL1, IGL1
  • Entrez Gene ID: 3543
  • Molecular mass of antigen [kDa]: 23
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, VioBright 515, Biotin
  • Selected references

    1. Hollis, G. F. et al. (1989) Immunoglobulin lambda light-chain-related genes 14.1 and 16.1 are expressed in pre-B cells and may encode the human immunoglobulin omega light-chain protein. Proc. Natl. Acad. Sci. U.S.A. 86(14): 5552-5556
    2. Bankovich, A. J. et al. (2007) Structural insight into pre-B cell receptor function. Science 316(5822): 291-294
Product options: 10
130-118-417

CD179b-PE, human

for 30
tests
(1)
-
130-118-263

CD179b-PE, human

for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-