CD102 (ICAM-2) antibodies, mouse

CD102 (ICAM-2) antibodies, mouse

Clone: REA745 | Dilution: 1:50
Clone REA745 recognizes the mouse CD102 antigen, also known as intercellular adhesion molecule 2 (ICAM-2). CD102 is a type I transmembrane glycoprotein belonging to the ICAM proteins of the Ig superfamily. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1. CD102 is found in endothelial cells and leukocytes and is expressed in high level in lung. CD102 plays a role in adhesive interactions, which are important for antigen-specific immune response, in NK-cell mediated clearance, and lymphocyte recirculation. Furthermore, CD102 is involved in other cellular interactions which are important for immune response and surveillance.
Additional information: Clone REA745 displays negligible binding to Fc receptors.

Alternative names

ICAM-2, ICAM2

Technical specifications

  • Antigen: CD102 (ICAM-2)
  • Clone: REA745
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: ICAM-2, ICAM2
  • Entrez Gene ID: 15896
  • Molecular mass of antigen [kDa]: 29
  • Distribution of antigen: endothelial cells, leukocytes, lung, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Xu, H. et al. (1992) Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA. J. Immunol. 149(8): 2650-2655
    2. Simmons, D. L. (1995) The role of ICAM expression in immunity and disease. Cancer Surv. 24: 144-155
    3. Casasnovas, J. M. et al. (1999) Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily. Proc. Natl. Acad. Sci. U.S.A. 96(6): 3017-3022
Product options: 8
30 µg in 200 µL (1)
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150 µg in 1 mL (1)
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30 µg in 200 µL (1)
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150 µg in 1 mL (1)
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30 µg in 200 µL (1)
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150 µg in 1 mL (1)
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30 µg in 200 µL (1)
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2×150 µg in 1 mL (1)
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