Anti-TCR Vβ5.3 antibodies, human

Anti-TCR Vβ5.3 antibodies, human

Clone: REA670 | Dilution: 1:11
Clone REA670 recognizes the human variable beta 5.3 subunit of the α/β T cell receptor (TCR Vβ5.3), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.3 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. TCR Vβ5.3 is expressed on a subset of peripheral blood T cells.
Additional information: Clone REA670 displays negligible binding to Fc receptors.

Alternative names

TCR Vbeta5.3, TCR Vb5.3

Technical specifications

  • Antigen: TCR Vβ5.3
  • Clone: REA670
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCR Vbeta5.3, TCR Vb5.3
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, Biotin
  • Selected references

    1. Born, W. et al. (1985) Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc. Natl. Acad. Sci. U.S.A. 82(9): 2925-2929
    2. Adari, H. et al. (1995)
      Expression of the human T-cell receptor V beta 5.3 in
      Escherichia coli
      by thermal induction of the trc promoter: nucleotide sequence of the lacIts gene.
      DNA Cell Biol. 14(11): 945-950
    3. Bleux, C. et al. (1995) A mouse monoclonal antibody specific for the V beta 5.3 chain of the human TcR recognizes a subgroup of the mouse TcR V beta 8.2 chains. J. Leukoc. Biol. 57(3): 491-491
Product options: 8
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
-