Anti-Mesothelin antibodies, human

Anti-Mesothelin antibodies, human

Clone: REA1057 | Dilution: 1:50
Clone REA1057 recognizes the human mesothelin antigen, a membrane glycoprotein also known as CAK1 or pre-pro-megakaryocyte-potentiating factor. Mesothelin is expressed on mesothelial cells and overexpressed on different tumors, e.g., mesotheliomas and adenocarcinomas. Mesothelin is a precursor protein which has functions in cellular adhesion.
Additional information: Clone REA1057 displays negligible binding to Fc receptors.

Alternative names

CAK1, MPF, MSLN

Technical specifications

  • Antigen: Mesothelin
  • Clone: REA1057
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CAK1, MPF, MSLN
  • Entrez Gene ID: 10232
  • Molecular mass of antigen [kDa]: 35
  • Distribution of antigen: tumor cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Hassan, R. et al. (2004) Mesothelin: a new target for immunotherapy. Clin. Cancer Res. 10(12 Pt 1): 3937-3942
    2. Onda, M. et al. (2006) Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma. Clin. Cancer Res. 12(14 Pt 1): 4225-4231
    3. Iwahori, K. et al. (2008) Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin. Lung Cancer 62(1): 45-54
Product options: 8
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for 30
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for 100
tests
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for 30
tests
(1)
-
for 100
tests
(1)
-
for 30
tests
(1)
-
for 100
tests
(1)
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