Anti-Frizzled-1 antibodies, mouse

Anti-Frizzled-1 antibodies, mouse

Clone: REA603 | Dilution: 1:50
Clone REA603 recognizes the mouse frizzled-1 antigen. Frizzled-1 is a member of the frizzled family of proteins which encode seven-transmembrane domain proteins that are receptors for the wingless-type MMTV integration site family of signaling proteins. Frizzled-1 is expressed primarily in the developing lung mesenchyme, in adult heart, placenta, kidney, pancreas, prostate, and ovary. Frizzled-1 interacts with Wnt7b.
Additional information: Clone REA603 displays negligible binding to Fc receptors.

Alternative names

Fz-1, Fzd1

Technical specifications

  • Antigen: Frizzled-1
  • Clone: REA603
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Fz-1, Fzd1
  • Entrez Gene ID: 8321, 14362
  • Molecular mass of antigen [kDa]: 64
  • Cross-reactivity: human
  • Distribution of antigen: heart, placenta, kidney, ovary, prostate cancer cells, pancreas
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Sagara, N. et al. (1998) Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7. Biochem. Biophys. Res. Commun. 252(1): 117-122
    2. Gazit, A. et al. (1999) Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response. Oncogene 18(44): 5959-5966
    3. Wang, Z. et al. (2005) Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Mol. Cell. Biol. 25(12): 5022-5030
Product options: 8
30 µg in 200 µL (1)
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150 µg in 1 mL (1)
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30 µg in 200 µL (1)
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150 µg in 1 mL (1)
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30 µg in 200 µL (1)
-
150 µg in 1 mL (1)
-
30 µg in 200 µL (1)
-
150 µg in 1 mL (1)
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