The Zika capsid protein C domain from virus subtype Z1106033 comprises the amino acids 1–127 of the full length polyprotein. The Zika virus belongs to the family of flaviviruses
and is spread by Aedes
mosquitos. In most cases no symptoms are observed after infection, but about 20% of Zika infected individuals react with symptoms like fever, red eyes, joint pain, and headache. During pregnancy the virus can spread to the fetus and cause microcephaly and other brain malformations. The virus is distributed in around 40 countries and the Aedes mosquitos can be found in all tropical and subtropical areas.