CD47 antibodies, mouse

CD47 antibodies, mouse

Clone: REA170 | Dilution: 1:10
Clone REA170 recognizes CD47, which is also known as integrin-associated protein. CD47 is a 50 KDa heavily glycosylated protein with an extracellular IgV domain, five transmembrane domains and a cytoplasmic tail, which exists in 4 different isoforms. The expression of CD47 varies in different tissue types depending upon the cytoplasmic tail isoform associated, for e.g the 16 amino acid form 2, is expressed in all cells of hematopoietic origin, endothelial and epithelial cells whereas 36 amino acids form 4 is expressed mainly in neurons, intestine, and testis. CD47 can interact with integrins, Thrombospondin-1 (TSP-1), cell surface gylcoproteins SIRPα and SIRPβ. Owing to these interactions, CD47 plays an important role in lymphocyte homeostasis, maturation and activation of dendritic cells, cellular transmigration and phagocytosis of cells.
Additional Information: Clone REA170 displays negligible binding to Fc receptors.

Alternative names

Integrin-associated protein, IAP, Itgp, CD47

Technical specifications

  • Antigen: CD47
  • Clone: REA170
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Integrin-associated protein, IAP, Itgp, CD47
  • Distribution of antigen: B cells, T cells, endothelial cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Demeure, C. E. et al. (2000) CD47 engagement inhibits cytokine production and maturation of human dendritic cells. J. Immunol. 164: 2193-2199
Product options: 16
130-103-109

CD47-FITC, mouse

9 µg in 300 µL (1)
JPY 3,800
130-102-538

CD47-FITC, mouse

30 µg in 1 mL (1)
JPY 7,500
130-103-108

CD47-PE, mouse

9 µg in 300 µL (1)
JPY 4,800
130-102-617

CD47-PE, mouse

30 µg in 1 mL (1)
JPY 12,000
130-103-111

CD47-APC, mouse

9 µg in 300 µL (1)
JPY 7,000
130-102-591

CD47-APC, mouse

30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 10,000
30 µg in 1 mL (1)
JPY 17,000
9 µg in 300 µL (1)
JPY 8,500
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 9,000
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 8,300
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 2,800
30 µg in 1 mL (1)
JPY 7,500

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