CD301a (MGL1) antibodies, mouse

CD301a (MGL1) antibodies, mouse

Clone: REA581 | Dilution: 1:10
Clone REA581 recognizes the mouse CD301a antigen, a type II transmembrane glycoprotein also known as macrophage galactose-type C-type lectin-1 (MGL1). CD301 has two genes, CD301a and CD301b, which are highly homologous. In contrast to CD301b, that recognizes N-acetylgalactosamine and galactose, including the O-linked Tn antigen, TF antigen, and core 2, CD301a is highly specific for Lewis X and Lewis A structures. It has been suggested that MGL1 is involved in the clearance of apoptotic cells. CD301a is expressed in alternatively activated macrophages.
Additional information: Clone REA581 displays negligible binding to Fc receptors.

Alternative names

Clec10a, MMGL, M-ASGP-BP-1

Technical specifications

  • Antigen: CD301a (MGL1)
  • Clone: REA581
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Clec10a, MMGL, M-ASGP-BP-1
  • Entrez Gene ID: 17312
  • Molecular mass of antigen [kDa]: 35
  • Distribution of antigen: macrophages
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Raes, G. et al. (2005) Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J. Leukoc. Biol. 77(3): 321-327
    2. Yuita, H. et al. (2005) Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos. Glycobiology 15(12): 1368-1375
    3. Singh, S. K. et al. (2009) Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties. Mol. Immunol. 46(6): 1240-1249
Product options: 10
9 µg in 300 µL (1)
JPY 6,800
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 4,800
30 µg in 1 mL (1)
JPY 14,000
9 µg in 300 µL (1)
JPY 7,000
30 µg in 1 mL (1)
JPY 14,000
9 µg in 300 µL (1)
JPY 8,500
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 2,800
30 µg in 1 mL (1)
JPY 8,000

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