CD28 antibodies, rat

CD28 antibodies, rat

Clone: REA206 | Dilution: 1:10
Clone REA206 recognizes rat CD28, a 44 kDa glycoprotein also known as Tp44. CD28 is a homodimeric type I transmembrane protein of the Ig receptor superfamily, composed of disulfide-linked subunits. It is a costimulatory molecule which is expressed on most thymocytes, CD4
+
and CD8
+
T cells, and NK cells. Expression of CD28 is down-regulated at late stages of terminal effector T cell differentiation. Ligation of CD28 with CD80 (B7-1) and CD86 (B7-2) provides a costimulatory signal for T cell activation.
Additional information: Clone REA206 displays negligible binding to Fc receptors.

Alternative names

CD28RNA

Technical specifications

  • Antigen: CD28
  • Clone: REA206
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CD28RNA
  • Entrez Gene ID: 25660
  • Molecular mass of antigen [kDa]: 23
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Clark, G. J. et al. (1992) Identification of a cDNA encoding the rat CD28 homologue. Immunogenetics 35(1): 54-57
    2. Guo, L. et al. (2003) Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation. Transpl Immunol. 12(1): 41-48
Product options: 10
130-103-333

CD28-FITC, rat

9 µg in 300 µL (1)
JPY 3,800
130-102-694

CD28-FITC, rat

30 µg in 1 mL (1)
JPY 7,500
130-103-332

CD28-PE, rat

9 µg in 300 µL (1)
JPY 4,800
130-102-693

CD28-PE, rat

30 µg in 1 mL (1)
JPY 12,000
130-103-331

CD28-APC, rat

9 µg in 300 µL (1)
JPY 7,000
130-102-692

CD28-APC, rat

30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 8,500
30 µg in 1 mL (1)
JPY 18,000
130-102-122

CD28-Biotin, rat

9 µg in 300 µL (1)
JPY 2,800
130-101-976

CD28-Biotin, rat

30 µg in 1 mL (1)
JPY 7,500

Related products

2 products available