CD263 (TRAIL-R3) antibodies, human

CD263 (TRAIL-R3) antibodies, human

Clone: DJR3 | Dilution: 1:11
Clone DJR3 recognizes the human CD263 antigen, a glycophospholipid-anchored cell membrane protein which is also known as TNF-related apoptosis-inducing ligand receptor 3 (TRAIL-R3) or tumor necrosis factor receptor superfamily member 10C (TNFRSF10C). CD263 is the receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain shared by several members of the TNF receptor superfamily and hence is not capable of inducing apoptosis. CD263 is highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung, and heart. It is higher expressed in normal tissues than in tumor cell lines.

Alternative names

TNFRSF10C, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID

Technical specifications

  • Antigen: CD263 (TRAIL-R3)
  • Clone: DJR3
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: TNFRSF10C, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
  • Entrez Gene ID: 8794
  • Molecular mass of antigen [kDa]: 22
  • Distribution of antigen: lymphocytes, spleen, skeletal muscle, placenta, lung, heart
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected references

    1. Mongkolsapaya, J. et al. (1998) Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL. J. Immunol. 160(1): 3-6
    2. Degli-Esposti, M. A. et al. (1997) Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family J. Exp. Med. 186(7): 1165-1170
    3. Ursini-Siegel, J. et al. (2007) Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development Mol. Cell. Biol. 27(18): 6361-6371
Product options: 6
for 30
tests
(1)
JPY 24,000
for 100
tests
(1)
JPY 57,000
for 30
tests
(1)
JPY 24,000
for 100
tests
(1)
JPY 57,000
for 30
tests
(1)
JPY 20,000
for 100
tests
(1)
JPY 49,000