CD200 antibodies, rat

CD200 antibodies, rat

Clone: REA532 | Dilution: 1:10
Clone REA532 recognizes the rat CD200 antigen, which is a transmembrane glycoprotein containing two extracellular immunoglobulin domains and lacks intracellular signaling motifs or docking sites for adapter signaling molecules. CD200, also known as MRC OX-2 antigen, is expressed on a variety of tissues, including the nervous system, activated T cells, B cells, dendritic cells in lymphatic follicles, cells of glomeruli and ovarian degenerating follicles, and vascular endothelium. It is also distributed at the epithelium-derived tissues such as the thymus, retinas, and hair follicles. CD200 interacts with CD200R, an immunoglobulin superfamily inhibitory receptor expressed primarily on myeloid/monocyte lineage cells, and has a suppressive effect on T cell–mediated immune response.
Additional information: Clone REA532 displays negligible binding to Fc receptors.

Alternative names

Cspmo2, MRCOX2, Mox2

Technical specifications

  • Antigen: CD200
  • Clone: REA532
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Cspmo2, MRCOX2, Mox2
  • Entrez Gene ID: 24560
  • Molecular mass of antigen [kDa]: 28
  • Distribution of antigen: T cells, B cells, dendritic cells, ovary, endothelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Clark, M. J. et al. (1985) MRC OX-2 antigen: a lymphoid/neuronal membrane glycoprotein with a structure like a single immunoglobulin light chain. EMBO J. 4(1): 113-118
    2. Barclay, A. N. et al. (1986) Neuronal/lymphoid membrane glycoprotein MRC OX-2 is a member of the immunoglobulin superfamily with a light-chain-like structure. Biochem. Soc. Symp. 51: 149-157
    3. Ya-Fen, J. S. et al. (2010) Distribution and expression of CD200 in the rat respiratory system under normal and endotoxin-induced pathological conditions. J. Anat. 216(3): 407-416
Product options: 14
130-108-125

CD200-FITC, rat

9 µg in 300 µL (1)
JPY 3,800
130-108-090

CD200-FITC, rat

30 µg in 1 mL (1)
JPY 7,500
130-108-126

CD200-PE, rat

9 µg in 300 µL (1)
JPY 4,800
130-108-091

CD200-PE, rat

30 µg in 1 mL (1)
JPY 12,000
130-108-127

CD200-APC, rat

9 µg in 300 µL (1)
JPY 7,000
130-108-092

CD200-APC, rat

30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 8,500
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 9,000
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 8,300
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 2,800
30 µg in 1 mL (1)
JPY 7,500

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