CD16/CD32 antibodies, mouse

CD16/CD32 antibodies, mouse

Clone: REA377 | Dilution: 1:50
Clone REA377 recognizes a shared epitope common to the human CD16 and CD32 antigens. CD16 and CD32 are also known as FcγIII and FcγII, respectively, and bind to epitopes located in the constant region domain of IgG. CD16 and CD32 are predominantly expressed on cells of hematopoietic lineages, including B cells, monocytes, NK cells, granulocytes, and dendritic cells. They are also found on hematopoietic progenitor cells, where they appear to play a role in T and B cell development.
Additional information: Clone REA377 displays negligible binding to Fc receptors.

Alternative names

Fc-gamma-RIIB, FCGR3, FcRIII, FcR-10, Fc-gamma RII, FcRII, Ly-17

Technical specifications

  • Antigen: CD16/CD32
  • Clone: REA377
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Fc-gamma-RIIB, FCGR3, FcRIII, FcR-10, Fc-gamma RII, FcRII, Ly-17
  • Entrez Gene ID: 14131, 14130
  • Molecular mass of antigen [kDa]: 26; 33
  • Distribution of antigen: B cells, monocytes, NK cells, granulocytes, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
  • Selected references

    1. de Andrés, B. et al. (1997) Fc gammaRII (CD32) is linked to apoptotic pathways in murine granulocyte precursors and mature eosinophils. Blood 90(3): 1267-1274
    2. de Andrés, B. et al. (1998) A regulatory role for Fcgamma receptors CD16 and CD32 in the development of murine B cells. Blood 92(8): 2823-2829
    3. Zhang, D. et al. (2014) CD16 inhibition increases host survival in a murine model of severe sepsis. J. Surg. Res. 187(2): 605-609
Product options: 2
30 µg in 200 µL (1)
JPY 12,000
150 µg in 1 mL (1)
JPY 35,000

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