CD158e/k (KIR3DL1/DL2) antibodies, human

CD158e/k (KIR3DL1/DL2) antibodies, human

Clone: REA970 | Dilution: 1:50
Clone REA970 recognizes the human CD158e (KIR3DL1) and CD158k (KIR3DL2) antigens, members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of KIR contributes to the regulation of NK cell–mediated cytotoxicity. Expression is found mainly on CD56
dim
CD16
+
natural killer (NK) cells but also on a subset of CD8
+
T cells. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs.
Additional information: Clone REA970 displays negligible binding to Fc receptors.

Alternative names

KIR3DL1, KIR3DL2

Technical specifications

  • Antigen: CD158e/k (KIR3DL1/DL2)
  • Clone: REA970
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR3DL1, KIR3DL2
  • Entrez Gene ID: 3811
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Yawata, M. et al. (2002) Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family. Crit. Rev. Immunol. 22(5–6): 463-482
    2. Uhrberg, M. (2005) The KIR gene family: life in the fast lane of evolution. Eur. J. Immunol. 35(1): 10-15
  • gentleMACS Protocols

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JPY 25,000
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JPY 59,000
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JPY 59,000
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tests
(1)
JPY 22,000
for 100
tests
(1)
JPY 52,000

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