CD155 antibodies, mouse

CD155 antibodies, mouse

Clone: REA519 | Dilution: 1:10
Clone REA519 recognizes the mouse CD155 antigen, which is a 70 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. CD155, also known as poliovirus receptor (PVR), belongs to a large family of Ig molecules called nectins and nectin-like proteins, which mediate cell-cell adhesion, cell migration, and serve as entry receptors for viruses. CD155 and its family member CD112 (nectin-2) are the ligands for the activating cell-surface receptor DNAM-1 on CD8
+
T cells and natural killer (NK) cells. Mouse CD155 is found on a wide variety of cells of hematopoietic origin, on CD4
+
CD8
+
thymocytes, regulatory T cells, other activated T cells, NKT cells, and at cell junctions on the primary vascular endothelial cells.
Additional information: Clone REA519 displays negligible binding to Fc receptors.

Alternative names

PVR, HVED, PVS, Taa1, TAGE4, mE4, NECL-5

Technical specifications

  • Antigen: CD155
  • Clone: REA519
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: PVR, HVED, PVS, Taa1, TAGE4, mE4, NECL-5
  • Entrez Gene ID: 52118
  • Molecular mass of antigen [kDa]: 45
  • Distribution of antigen: endothelial cells, T cells, T helper cells, NKT cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Fuchs, A. et al. (2004) Cutting Edge: CD96 (Tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J. Immunol. 172: 3994-3998
    2. Tahara-Hanaoka, S. et al. (2006) Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor. Blood 107: 1491-1496
    3. Seth, S. et al. (2007) The murine pan T cell marker CD96 is an adhesion receptor for CD155 and nectin-1. Biochem. Biophys. Res. Commun. 364(4): 959-965
Product options: 10
9 µg in 300 µL (1)
JPY 6,800
30 µg in 1 mL (1)
JPY 18,000
130-107-860

CD155-PE, mouse

9 µg in 300 µL (1)
JPY 4,800
130-107-807

CD155-PE, mouse

30 µg in 1 mL (1)
JPY 12,000
130-107-861

CD155-APC, mouse

9 µg in 300 µL (1)
JPY 7,000
130-107-808

CD155-APC, mouse

30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 8,500
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 2,800
30 µg in 1 mL (1)
JPY 7,500

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