CD117 antibodies, mouse

CD117 antibodies, mouse

Clone: REA791 | Dilution: 1:50
Clone REA791 recognizes the mouse CD117 antigen, a 145 kDa cell surface glycoprotein belonging to the class III receptor tyrosine kinase family. CD117 is also known as c-kit or stem cell factor (SCF) receptor. It is expressed on the majority of hematopoietic progenitor cells including multipotent hematopoietic stem cells as well as some committed myeloid, erythroid and lymphoid precursor cells, and mature mast cells. CD117
+
stem cells from murine bone marrow could also be differentiated into smooth muscle cells, myocytes, and endothelial cells
in vivo
.
Additional information: Clone REA791 displays negligible binding to Fc receptors.

Alternative names

c-kit, SCO1, SCO5, SOW3, Ssm, Tr-kit, KIT, W, SCFR

Technical specifications

  • Antigen: CD117
  • Clone: REA791
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: c-kit, SCO1, SCO5, SOW3, Ssm, Tr-kit, KIT, W, SCFR
  • Entrez Gene ID: 16590
  • Molecular mass of antigen [kDa]: 107
  • Distribution of antigen: B cells, bone marrow, brain, cancer stem cells, dendritic cells, endothelial cells, fibroblasts, hematopoietic stem cells, kidney, leukemia cells, liver, lung, mast cells, megakaryocytes, myeloid cells, NK cells, red blood cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, VioBright 515, Biotin
  • Selected references

    1. Qiu, F. H. et al. (1998) Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J. 7(4): 1003-1011
    2. Orlic, D. (2002) Stem cell repair in ischemic heart disease: an experimental model. Int. J. Hematol. 76(suppl.1): 144-145
    3. Zayas, J. et al. (2008) Murine hematopoietic stem cells and multipotent progenitors express truncated intracellular form of c-kit receptor. Stem Cells Dev. 17(2): 343-353
Product options: 8
130-111-693

CD117-PE, mouse

30 µg in 200 µL (1)
JPY 9,500
130-111-615

CD117-PE, mouse

150 µg in 1 mL (1)
JPY 28,000
130-111-694

CD117-APC, mouse

30 µg in 200 µL (1)
JPY 9,500
30 µg in 200 µL (1)
JPY 18,000
30 µg in 200 µL (1)
JPY 25,000
150 µg in 1 mL (1)
JPY 73,000
30 µg in 200 µL (1)
JPY 7,000
150 µg in 1 mL (1)
JPY 20,000

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