Anti-TCR Vβ3 antibodies, mouse

Anti-TCR Vβ3 antibodies, mouse

Clone: REA646 | Dilution: 1:10
Clone REA646 recognizes the mouse V beta 3 T cell receptor (TCR Vβ3). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ3 is a variant of the TCR β chain and is expressed on T cells having the a, b, and c haplotype of the TCR β gene complex.
Additional information: Clone REA646 displays negligible binding to Fc receptors.

Alternative names

TCR Vb3, Gm2426, Tcrb-V16

Technical specifications

  • Antigen: TCR Vβ3
  • Clone: REA646
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCR Vb3, Gm2426, Tcrb-V16
  • Entrez Gene ID: 100039790
  • Molecular mass of antigen [kDa]: 11
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Fairchild, S. et al. (1992)
      Tcrb-V3
      +
      T-cell deletion and a new mouse mammary tumor provirus, Mtv-44.
      Immunogenetics 36(3): 189-194
    2. Tomonari, K. et al. (1992)
      Tcrb-V3
      +
      T-cell deletion and a mouse mammary tumor provirus, Mtv-27.
      Immunogenetics 36(5): 302-305
    3. Lee, J. S. et al. (2006)
      Antigen-specific expansion of TCR Vbeta3
      +
      CD4
      +
      T cells in the early stage of collagen-induced arthritis and its arthritogenic role in DBA/1J mice.
      J. Clin. Immunol. 26(3): 204-212
Product options: 11
9 µg in 300 µL (1)
JPY 6,800
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 4,800
30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 7,000
30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 8,500
30 µg in 1 mL (1)
JPY 18,000
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 2,800
30 µg in 1 mL (1)
JPY 7,500