Anti-TCR Vβ17a antibodies, mouse

Anti-TCR Vβ17a antibodies, mouse

Clone: REA647 | Dilution: 1:10
Clone REA647 recognizes the mouse V beta 17a T cell receptor (TCR Vβ17a). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ17a is a variant of the TCR β chain and is expressed on T cells having the a haplotype (eg. C57L, SJL, SWR) of the TCRβ gene complex.
Additional information: Clone REA647 displays negligible binding to Fc receptors.

Alternative names

TCR Vbeta17a, Gm16779, Tcrb-V9

Technical specifications

  • Antigen: TCR Vβ17a
  • Clone: REA647
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCR Vbeta17a, Gm16779, Tcrb-V9
  • Entrez Gene ID: 100124681
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, Biotin
  • Selected references

    1. McDuffie, M. et al. (1992)
      I-E-independent deletion of V beta 17a
      +
      T cells by Mtv-3 from the nonobese diabetic mouse.
      J. Immunol. 148(7): 2097-9102
    2. Kuchroo, V. K. et al. (1992) Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage. J. Immunol. 148(12): 3776-3782
    3. Katz, J. et al. (1994)
      Expression of superantigen-like specificities on murine sjl/j-B lymphomas - antitumor v-Beta-17a
      +
      T-lymphocytes use a diverse set of T-cell receptor v-alpha-chain gene-sequences.
      Int. J. Oncol. 4(4): 839-847
Product options: 4
9 µg in 300 µL (1)
JPY 4,800
30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 2,800
30 µg in 1 mL (1)
JPY 7,500

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