Anti-TCR Vβ11 antibodies, mouse

Anti-TCR Vβ11 antibodies, mouse

Clone: REA657 | Dilution: 1:10
Clone REA657 recognizes the mouse V beta 11 T cell receptor (TCR Vβ11). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRγ/δ T cells. TCR Vβ11 is a variant of the TCR β chain and is expressed on mouse strains with the b haplotype in the TCR β gene complex, including C57BL/6 and B10, but not on mice strains with the a haplotype, including C57L, SJL, and SWR.
Additional information: Clone REA657 displays negligible binding to Fc receptors.

Alternative names

TCR Vb11, TCR Vbeta11

Technical specifications

  • Antigen: TCR Vβ11
  • Clone: REA657
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCR Vb11, TCR Vbeta11
  • Entrez Gene ID: 100124671
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Bill, J. et al. (1989) The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells. J. Exp. Med. 169(4): 1405-1419
    2. Davis, M. M. et al. (1998) Ligand recognition by alpha beta T cell receptors. Annu. Rev. Immunol. 16: 523-544
    3. DiRienzo, C. G. et al. (2007)
      T-cell receptor V(alpha) usage by effector CD4
      +
      Vbeta11
      +
      T cells mediating graft-versus-host disease directed to minor histocompatibility antigens.
      Biol. Blood Marrow Transplant. 13(3): 265-276
Product options: 16
9 µg in 300 µL (1)
JPY 3,800
30 µg in 1 mL (1)
JPY 7,500
9 µg in 300 µL (1)
JPY 4,800
30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 7,000
30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 10,000
30 µg in 1 mL (1)
JPY 17,000
9 µg in 300 µL (1)
JPY 8,500
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 9,000
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 8,300
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 2,800
30 µg in 1 mL (1)
JPY 7,500

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