Anti-TCR Vα3.2 (b, c) antibodies, mouse

Anti-TCR Vα3.2 (b, c) antibodies, mouse

Clone: REA395 | Dilution: 1:10
Clone REA395 recognizes the mouse Vα 3.2 T cell receptor (TCR Vα3.2) of mice having the b (e.g., C57BL/6) and c (e.g., SJL, NOD) haplotypes, but not with the strains having the a (Balb/c) or d (DBA/2) haplotype. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vα elements are expressed preferentially in CD4 or CD8 subsets in a manner that is largely independent of the MHC haplotype. It is likely that the Vα elements interact preferentially with conserved regions of class I or class II molecules.
Additional information: Clone REA395 displays negligible binding to Fc receptors.

Alternative names

TCRA, TCR Va3.2, TCR-Va3.2

Technical specifications

  • Antigen: TCR Vα3.2 (b, c)
  • Clone: REA395
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCRA, TCR Va3.2, TCR-Va3.2
  • Entrez Gene ID: 21473
  • Molecular mass of antigen [kDa]: 16
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Sim, B. C. et al. (1997) V alpha 3.2 selection in MHC class I mutant mice: evidence for an alternate orientation of TCR-MHC class I interaction. J. Immunol. 159(7): 3322-3329
    2. Pereira, P. et al. (1997) The T cell receptor repertoire of intestinal intraepithelial gammadelta T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci. Proc. Natl. Acad. Sci. U.S.A. 94(11): 5761-5766
    3. von Essen, M. R. et al. (2012) Mechanisms behind functional avidity maturation in T cells. Clin. Dev. Immunol. 2012: 163453
Product options: 16
9 µg in 300 µL (1)
JPY 3,800
30 µg in 1 mL (1)
JPY 7,500
9 µg in 300 µL (1)
JPY 4,800
30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 7,000
30 µg in 1 mL (1)
JPY 12,000
9 µg in 300 µL (1)
JPY 10,000
30 µg in 1 mL (1)
JPY 17,000
9 µg in 300 µL (1)
JPY 8,500
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 9,000
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 8,300
30 µg in 1 mL (1)
JPY 18,000
9 µg in 300 µL (1)
JPY 2,800
30 µg in 1 mL (1)
JPY 7,500

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