Anti-Prominin-1 antibodies, mouse

Anti-Prominin-1 antibodies, mouse

Clone: MB9-3G8 | Dilution: 1:50
Clone MB9-3G8 specifically recognizes the mouse prominin-1 antigen, a glycoprotein with close structural similarity to its human ortholog, CD133. Prominin-1 is expressed on neural stem cells, for example, in the white matter of the cerebellum, on neuroepithelial tissue cells, and on various other epithelial cells in the mouse embryo. 5–10% of the neural cells found in the subventricular zone of postnatal mice have been shown to be prominin-1-positive. In the adult mouse, prominin-1 has been detected in the brain ependymal layer and in kidney tubules.

Alternative names

PROM1, AC133, CD133

Technical specifications

  • Antigen: Prominin-1
  • Clone: MB9-3G8
  • Isotype: rat IgG1
  • Isotype control: Rat IgG1 – isotype control antibodies
  • Alternative names of antigen: PROM1, AC133, CD133
  • Entrez Gene ID: 19126
  • Molecular mass of antigen [kDa]: 95
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
  • Selected references

    1. Weigmann, A. et al. (1997) Prominin, a novel microvilli-specific polytopic membrane proteine of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 94: 12425-12430
    2. Singh, S.K. et al. (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res. 63: 5821-5828
    3. Lee, A. et al. (2005) Isolation of neural stem cells from the postnatal cerebellum. Nat. Neurosci. 8: 723-729
    4. Corbeil, D. et al. (2001) Prominin: a story of cholesterol, plasma membrane protrusions and human pathology. Traffic 2: 82-91
  • Brochures and posters

Product options: 1
30 µg in 200 µL (1)
JPY 12,000

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