Anti-IL-21 antibodies, human

Anti-IL-21 antibodies, human

Clone: 3A3-N2 | Dilution: 1:50
Interleukin 21 (IL-21) is secreted by a certain subset of CD4
+
T cells, called T follicular helper (Tfh) cells, also characterized by the expression of CXCR5 and ICOS and the lineage-specific transcription factor BCL6. But IL-21 production can also be found in other T helper (Tʜ) cell lineages and natural killer T (NKT) cells. IL-21 acts in a autocrine manner on Tfh cells and is critical for antibody production by B cells, it enhances natural killer (NK) cell functions, and promotes proliferation of CD8
+
T cells.

Alternative names

CVID11, Za11

Technical specifications

  • Antigen: IL-21
  • Clone: 3A3-N2
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CVID11, Za11
  • Entrez Gene ID: 59067
  • Molecular mass of antigen [kDa]: 15
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC
Product options: 2
for 30
tests
JPY 24,000
for 100
tests
JPY 57,000

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