Anti-IFN-γ antibodies, human

Anti-IFN-γ antibodies, human

Clone: REA600 | Dilution: 1:50
Clone REA600 recognizes the human interferon gamma (IFN-γ) antigen, a cytokine of type II class interferons. IFN-γ is produced by lymphocytes that are involved in inflammatory immune responses. It functions as a potent activator of macrophages, increases the antiviral and antitumor effects of the type I interferons, and has antiproliferative effects on transformed cells. IFN-γ is predominantly released by memory and effector CD4
+
and CD8
+
T cells as well as by NK cells upon activation.
Additional information: Clone REA600 displays negligible binding to Fc receptors.

Alternative names

IFN-gamma, Immune interferon

Technical specifications

  • Antigen: IFN-γ
  • Clone: REA600
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: IFN-gamma, Immune interferon
  • Entrez Gene ID: 3458
  • Molecular mass of antigen [kDa]: 16
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon,
    pigtail monkey (
    Macaca nemestrina
    )
    ,
    african green monkey (
    Chlorocebus aethiops
    )
    ,
    sooty mangabey (
    Cercocebus atys
    )
  • Distribution of antigen: macrophages, T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, VioBlue
  • Selected references

    1. Gray, P. W. et al. (1982) Structure of the human immune interferon gene. Nature 298(5877): 859-863
    2. Green, J. A. et al. (1969) Immune specific induction of interferon production in cultures of human blood lymphocytes. Science 164(3886): 1415-1417
    3. Schoenborn, J. R. et al. (2007) Regulation of interferon-gamma during innate and adaptive immune responses. Adv. Immunol. 96: 41-101
Product options: 12
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tests
(1)
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tests
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JPY 57,000
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JPY 24,000
for 100
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JPY 57,000
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JPY 25,000
for 100
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(1)
JPY 59,000
for 30
tests
(1)
JPY 25,000
for 100
tests
(1)
JPY 59,000
for 30
tests
(1)
JPY 24,000
for 100
tests
(1)
JPY 58,000

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