The antibody is suitable for ex vivo
T cell activation and expansion and is already established in a variety of clinical protocols for ex vivo
T cell stimulation. For example, the transduction of T cells with viral vectors requires the previous activation, which can be achieved by stimulation with CD3 antibody1,2
. Furthermore, T cell subsets, such as tumor infiltrating lymphocytes (TILs) can be expanded3
, or T cells polyclonally activated by CD3 stimulation.