Clone:
W5C5
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
BK65A6.2, MSC, W5C5

Specifications for SUSD2 Antibody, anti-human

Overview

Clone W5C5 recognizes the human sushi domain-containing protein 2 (SUSD2) antigen, a single-pass type I membrane protein which is expressed by bone marrow mesenchymal stem cells (MSCs), vessel-surrounding smooth muscle cells, and a few neoplastic cell lines. MSCs are multipotent stromal cells in various adult tissues that can replicate as undifferentiated cells and that have the potential to differentiate to lineages of mesenchymal tissues, including bone, cartilage, fat, tendon, muscle, and marrow stroma. Their application in numerous cases demonstrate their potential in the regeneration of all skeletal tissues, as well as of soft tissue organs. One particular advantage of MSCs is that they can be used when cells from the target tissue for regeneration are not available. SUSD2 expressing cells reside predominantly in a perivascular location in both basal and functional layers of endometrium. They are able to differentiate into adipocytes, osteocytes, chondrocytes, myocytes, and endothelial cells. SUSD2 is a single marker capable of purifying MSC and reconstituting endometrial stromal tissues
in vivo
.

Alternative names

BK65A6.2, MSC, W5C5

Detailed product information

Technical specifications

CloneW5C5
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenSUSD2
Alternative names of antigenBK65A6.2, MSC, W5C5
Molecular mass of antigen [kDa]88
Distribution of antigenstem cells, mesenchymal stem cells
Entrez Gene ID56241
RRIDAB_2733897, AB_2752221, AB_2752220, AB_2733896

Resources for SUSD2 Antibody, anti-human

References for SUSD2 Antibody, anti-human

Publications

  1. Masuda, H. et al. (2012) A novel marker of human endometrial mesenchymal stem-like cells. Cell Transplant 21(10): 2201-2214
  2. Ulrich, D. et al. (2014) Mesenchymal stem/stromal cells in post-menopausal endometrium. Hum. Reprod. 29(9): 1895-1905
  3. Benz, K. et al. (2013)
    Maintenance of "stem cell" features of cartilage cell sub-populations during
    in vitro
    propagation.
    J. Transl. Med. 11: 27

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