Background information
Clone IB6 recognizes the human CD38 antigen, a cell surface protein that exhibits receptor and enzymatic functions. This protein is highly expressed on plasma cells and expressed at lower levels on various hematopoietic and solid tissues. In the immune system CD38 plays a role in adhesion and transmigration through the endothelial layer. In addition, it can trigger the activation and proliferation of leukocytes. CD38 has cyclase as well as hydrolase activity.
Quality statement
MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.
