CD64 antibodies, human

CD64 antibodies, human

Clone: REA978 | Dilution: 1:50
Clone REA978 recognizes the human CD64 antigen, a high affinity Fc receptor for IgG, also known as FcγRI. CD64 contains three Ig-like domains in its extracellular domain and binds both monomeric and aggregated IgG and contributes to antibody-dependent cellular cytotoxicity (ADCC), phagocytosis, and the clearance of immune complexes. It is constitutively expressed on macrophages, monocytes, and eosinophils and can be up-regulated on neutrophils during infection or after stimulation with IFN-γ and colony-stimulating factors G-CSF and GM-CSF.
Additional information: Clone REA978 displays negligible binding to Fc receptors.

Alternative names

FCGR1A, CD64A, FcR I, IGFR1, FcγRI

Technical specifications

  • Antigen: CD64
  • Clone: REA978
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FCGR1A, CD64A, FcR I, IGFR1, FcγRI
  • Entrez Gene ID: 2209
  • Molecular mass of antigen [kDa]: 41
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon, capuchin monkey,
    squirrel monkey (
    Saimiri sciureus
    )
  • Distribution of antigen: granulocytes, macrophages, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Shen, L. et al. (1987) Polymorphonuclear leukocyte function triggered through the high affinity Fc receptor for monomeric IgG. J. Immunol. 139(2): 534-538
    2. Buckle, A. M. and Hogg, N. (1989) The effect of IFN-gamma and colony-stimulating factors on the expression of neutrophil cell membrane receptors. J. Immunol. 143(7): 2295-2301
    3. Herra, C. et al. (1996) Increased expression of Fc gamma receptors on neutrophils and monocytes may reflect ongoing bacterial infection. J. Med. Microbiol. 44(2): 135-140
Product options: 20
130-116-298

CD64-FITC, human

for 30
tests
(1)
EUR  85,00
130-116-195

CD64-FITC, human

for 100
tests
(1)
EUR  205,00
130-116-299

CD64-PE, human

for 30
tests
(1)
EUR  110,00
130-116-196

CD64-PE, human

for 100
tests
(1)
EUR  275,00
130-116-300

CD64-APC, human

for 30
tests
(1)
EUR  110,00
130-116-197

CD64-APC, human

for 100
tests
(1)
EUR  275,00
for 30
tests
(1)
EUR  135,00
for 100
tests
(1)
EUR  320,00
for 30
tests
(1)
EUR  135,00
for 100
tests
(1)
EUR  320,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  85,00
for 100
tests
(1)
EUR  205,00

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