CD49b antibodies, human

CD49b antibodies, human

Clone: REA188 | Dilution: 1:11
Clone REA188 recognizes CD49b, also known as integrin α2 chain. CD49b is single-pass, 150 KDa, type I membrane protein. Together with integrin β1 (CD29), CD49b forms the VLA-2 receptor, which binds ligands such as collagen, fibrinogen, and laminin and thus mediate the attachment of several cell types to extracellular matrix. Expression of CD49b is found on lymphocytes, activated T cells, monocytes, epithelial cells, and platelets.
Additional information: Clone REA188 displays negligible binding to Fc receptors.

Alternative names

Itga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α

Technical specifications

  • Antigen: CD49b
  • Clone: REA188
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Itga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α
  • Entrez Gene ID: 3673
  • Molecular mass of antigen [kDa]: 126
  • Distribution of antigen: monocytes, platelets, megakaryocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Elices, M. J., et al. (1989) The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others. Proc. Natl. Acad. Sci. U.S.A. 86: 9906-9910
Product options: 10
for 30
tests
(1)
EUR  105,00
for 100
tests
(1)
EUR  260,00
130-100-331

CD49b-PE, human

for 30
tests
(1)
EUR  125,00
130-100-333

CD49b-PE, human

for 100
tests
(1)
EUR  310,00
130-100-348

CD49b-APC, human

for 30
tests
(1)
EUR  125,00
130-100-396

CD49b-APC, human

for 100
tests
(1)
EUR  310,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  105,00
for 100
tests
(1)
EUR  260,00

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