CD30 antibodies, human

CD30 antibodies, human

Clone: REA1085 | Dilution: 1:50
Clone REA1085 recognizes the human CD30 antigen, a cell membrane protein, which is a member of the tumor necrosis factor receptor (TNFR) superfamily, and also known as Ki-1. CD30 is used as a tumor marker and is found on Hodgkin/Reed-Sternberg (H/RS) cells, embryonal carcinoma cells, and on activated T and B lymphocytes. It functions as a receptor for TNFSF8/CD30L and is involved in the regulation of cellular growth and transformation of activated lymphoblasts and regulates signal transduction by activation of NF-κB.
Additional information: Clone REA1085 displays negligible binding to Fc receptors.

Alternative names

TNFRSF8, Ki-1, Ber-H2

Technical specifications

  • Antigen: CD30
  • Clone: REA1085
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TNFRSF8, Ki-1, Ber-H2
  • Entrez Gene ID: 943
  • Molecular mass of antigen [kDa]: 62
  • Distribution of antigen: B cells, T cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin, FITC, PE, APC, VioBlue
  • Selected references

    1. Lee, S. Y. et al. (1996) T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors. J. Exp. Med. 183(2): 669-674
    2. Aizawa, S. et al. (1997) Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation. J. Biol. Chem. 272(4): 2042-2045
    3. Kimmig, S. et al. (2002) Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195: 789-794
Product options: 20
130-118-436

CD30-FITC, human

for 30
tests
(1)
EUR  105,00
130-118-282

CD30-FITC, human

for 100
tests
(1)
EUR  260,00
130-118-437

CD30-PE, human

for 30
tests
(1)
EUR  125,00
130-118-283

CD30-PE, human

for 100
tests
(1)
EUR  310,00
130-118-438

CD30-APC, human

for 30
tests
(1)
EUR  125,00
130-118-284

CD30-APC, human

for 100
tests
(1)
EUR  310,00
for 30
tests
(1)
EUR  135,00
for 100
tests
(1)
EUR  320,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  175,00
for 100
tests
(1)
EUR  420,00
for 30
tests
(1)
EUR  105,00
for 100
tests
(1)
EUR  260,00

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