CD28 antibodies, mouse

CD28 antibodies, mouse

Clone: REA806 | Dilution: 1:50
Clone REA806 recognizes the mouse CD28 antigen, a costimulatory molecule, expressed on most thymocytes, CD4
+
and CD8
+
T cells, and NK cells. Expression is down-regulated at late stages of terminal effector T cell differentiation. CD28 is a homodimeric type I transmembrane protein of the Ig receptor superfamily, composed of disulfide-linked 45 kDa subunits. Ligation of CD28 with CD80 (B7-1) and CD86 (B7-2) provides a costimulatory signal for T cell activation.
Additional information: Clone REA806 displays negligible binding to Fc receptors.

Alternative names

T44, Tp44

Technical specifications

  • Antigen: CD28
  • Clone: REA806
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: T44, Tp44
  • Entrez Gene ID: 12487
  • Molecular mass of antigen [kDa]: 23
  • Distribution of antigen: B cells, lymphocytes, plasma cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected references

    1. Gross, J. A. et al. (1990) The murine homologue of the T lymphocyte antigen CD28. Molecular cloning and cell surface expression. J. Immunol. 144(8): 3201-3210
    2. Harper, K. et al. (1991) CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J. Immunol. 147(3): 1037-1044
Product options: 5
130-111-972

CD28-PE, mouse

30 µg in 200 µL (1)
EUR  90,00
130-111-819

CD28-PE, mouse

150 µg in 1 mL (1)
EUR  265,00
130-111-973

CD28-APC, mouse

30 µg in 200 µL (1)
EUR  90,00
130-111-820

CD28-APC, mouse

150 µg in 1 mL (1)
EUR  265,00
30 µg in 200 µL (1)
EUR  50,00

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